I know it's best to get nutrients/effects from food/behavior, but depending on the style of my life at any given moment, it can be challenging to sun my balls everyday so to speak.
After reading Lifespan, I grew quite convinced of The Information Theory of Aging and have dabbled some in sirtuin-activating compounds. While I'd probably see more benefit from sleeping well, exercising more regularly, eating fewer dosas y less queso, failing with lower stakes, and having a chill jobbie, I've started to take both NMN and resveratrol again. It's also less about fighting aging directly for me and more about self-experimentation and improving performance. I find this kind of thing fun.
Otherwise, I go out of my way to eat sardines and oysters for Omega-3's and harder to come by minerals and cod liver for vitamin D when I'm unable to spend most of the day outside. I also bought some Methylene Blue recently out of curiosity and Nattokinase because I have familial history of Alzheimers.
Do you supplement with anything? What and why?
I also recommend Healthspan by Peter Attia. His take is that diet is somewhat meaningless of a thing to try to optimize if you haven't first mastered building an exercise routine.
All that said, I take a lot of things.
I start with
Then I follow it up for brunch, daily around 10:30-11am with a smoothy, which is
Then I do:
and after dinner:
I think that's all of it... I should make a full post at some point with the powder mixes and how I store them...
But... Why? Does it really make you feel that much better?
It's hard to say which of the things are the most important for that, but yes, I've tried a lot of different breakfast routines and with this one, I pack a big punch at brunch and I'm not hungry until dinner, so I get 2 meals a day but plenty of protein and nutrients. Some of these are not for the feel, like Lion's Mane: https://www.healthline.com/health-news/latest-study-suggests-lions-mane-mushrooms-may-boost-brain-heath
I have a lower score on my brain age compared to the rest of my biological age test results so I'm working on that.
Ultimately, doing a routine like this could be a waste of time if you aren't also taking regular bio tests (age, blood, etc) and verifying that all your stats are in order. Unfortunately, we don't live long enough to really put these all through a long-term individual variable test, so a lot of these are combined in a sort of best-guess crapshoot and I add/remove something about every 6-12 months based on latest research and test results.
Expand on those bio-tests; where can you do those and what are they called specifically, and how are they taken?
There are DNA methylation age tests like Elysium Index, and TallyHealth. But caveats:
There's also GlycanAge, which measures Glycans instead of Methylation. And there's TruAge that measures other things...
Probably more reliable metrics are blood tests that you can order through a doctor or online lab to get things like Apo B, general hormone levels, all the chemicals, etc. Again though, we aren't at the time of humanity where these are rapidly available enough to do weekly/monthly to get actionable/timely feedback. Hopefully we'll get there over the next few years (it's a lot better than it was).
As a first step, you can go to your general physician and just say that you haven't had a blood workup in a while and you want to make sure your hormones and other levels are ok. Mention Apo B or they might leave that out of the basic test. Or you can search online for biomarker tests and see what you find.
some of these are definitely pokémon, right?
Cordyceps wiped out another branch in the timeline.
https://m.stacker.news/13852
You asked on refilling day. I keep 21 of these CoaGu food grade steel storage containers on hand. I can easily throw 7 of them into a suitcase for a week trip and buy the olive oil and nut milk on the other side of the plane drop.
Forgot I recently added cranberry juice powder and more mushrooms
https://m.stacker.news/13858
I use a hand mixer so I can travel with it easily. I always make it in this big yeti mug. So if I’m on a travel day, I can get an oleato latte from Starbucks, pour my powder on top and mix it at the airport.
Hot damn
I wasn’t familiar with your game
Why NR and not NMN?
I used to take NMN, but some asshat biotech company filed it as a drug with the FDA so now you have to buy it out of country or with a prescription so my source stopped. Haven't found a new source. Do you nave one?
Toniiq still sells it directly on their website.
hadn't heard of them... will check it out
King
😳
so manny
Im not really precise or regular with any of this stuff, which probably helps from overdosing?? idk 🤷 do your own research etc etc
I generally try to work nutrients into my diet rather than supplementing. There are two supplements that I think most people need to take, though, in order to get optimal amounts:
I'd add some w-3 as a "you almost certainly need to supplement this" category.
Because modern diets are so inflammatory or because they're so high in omega 6?
Both.
I go out of my way to get a high w-3 balance in my diet. Do you think I might be overlooking something?
If you're making an effort you're probably doing pretty well.
Last I checked into this in any depth, there was a massive amount of disagreement over what w-3 levels should be, esp given current w-6 levels, esp given nutrient leaching due to industrial food production (cmp w-3 content in game vs industrial meat, for instance), esp given other pro-inflammatory covariates of modern industrialized lifestyles. Nutrition science is nearly the most thankless of all the quasi-sciences, so I certainly don't know the truth.
I just thought of this, but: are you making an exception to veganism wrt w-3 supplementation, or do you get some vegetable source of it? I'd be curious what that is, if the latter. That might be a thing to consider making an exception over, since my vague sense from having looked into this deeply twenty years ago is that vegetable versions would be drastically sub-optimal; but again, talking 65% out of my ass here.
The highest w-3 foods are flax and chia seeds. Some other nuts and seeds have really good w-3/w-6 ratios.
My understanding is that the ratio is most important, but like you say it's hard to pin that down very accurately. The most common number I see is 1:4, but I recall seeing 1:1.6. Since my diet is not very inflammatory I'm ok with targeting the 1:4.
You're right that plant sources are sub-optimal, but our bodies are capable of converting between the different forms of w-3. With the quantity of w-3 I consume, I'm pretty sure I'm producing sufficient levels of those particular forms.
Ah, it's coming back to me. When I left the discussion, the hot topic was how much of the plant-based w-3 really could be converted, with opinions varying drastically and the research being called into question / accused of being inapplicable for assorted reasons. (One of the reasons was that one camp viewed this not as a fixed conversion rate, but as dynamic and adaptive.)
Not to reignite controversy, but I'm curious if you feel anything from it? It's remarkable to me how much I do feel the psychotropic effects of smallish amounts of w-3 in concentrated fish-oil form. It's possible it's placebo, but I don't get the feeling from actual fatty fish, which is interesting. But it's strong enough for me that I take it in the evening to calm down and get ready for bed. Doesn't work w/ flaxseed oil, either. I'm quite sensitive to mind-altering substances, though.
maybe that's why Nutritional Yeast is so awesome for getting B-vitamins.
We go through a ton of nutritional yeast. Even so, I think it's best to take a B-12 supplement.
I was taking Vitamin D/k pills because it’s low and I need to get some sun. Now I’ve stopped taking them and I just work on sitting outside more and work from my laptop outside. There’s something about taking pills for things we could probably get naturally from the food we eat that makes me feel ehhh.
for the majority of the population, we're at a point in society, that it's mathematically impossible to get everything we need from food & life. they have done so much you wouldn't believe to our food supply, etc. and so much more. I digress, we're at a point, that supplements are really necessary.
Okay, not directly asking OP; an open question:
Why? Why do some of you take, like, 25 different sups?
I've experimented with those, too, but to me it was more of a "psychological" thing, with creatine and Pre-work out as one of the very few exemptions of sups that I really felt.
I can't imagine that you really feel each of those sups making a difference, or do they?
Even if the effects aren't felt, most of these things have purported theoretical benefits. Things can matter and not be felt, right?
That's the same as if I'd be looking at my dick exclusively from a specific beneficial angle; in theory it's bigger, but girls will still look funny at the little dragon...
The only difference between the above and taking sups is the price tag of the latter, innit?
a. it shouldn't look like a dragon. b. no that isn't a matched analogy
You're effectively saying you can't be poisoned so long as each time you take the poison you don't notice. If that's absurd, so is the idea that for things to have a benefit you must consciously and viscerally experience the benefit.
i’m kind of surprised by two things:
i’m way out of the loop on the latest biohacking/longevity stuff
Trying to eat more yogurt/probiotics & fiber to be more regular, but the berberine seems to be helping there.
Berberine is also supposed to be amazing for Insulin-Resistance and Diabetes. D3 is KEY in supplementation, for many reasons even beyond "immunity".
nothing for me, but i have made a conscious effort to eat much better food over the last year
Vitamins D3 from october to march for sure… Omega 3 is good but people tend to forget that omegas have to be balanced in the right proportion with Omegass 3 , 6 and 9 in order to be healthy !!! So careful with Omega 3 excess !
Vitamin D Vitamin C Zinc Sildenafil Quinine Liver Oysters Iodine Boron Fish Oil
Lot of D3, magnesium, zinc, NAC, black seed oil and creatine
diet is pretty protein/fat focused and aim to include a lot of fermented items
mainly for overall health and fitness but I haven’t been sick in a long time so hesitant to change anything
What’s methylene blue supposed to help with? Seeing that pop up more recently
I heard it helped with "energy" vaguely. Whatever that means. It's been used as a placebo so it might be useful to take if you're looking a placebo effect which can be a pretty worthwhile thing to look for.
Patients ask me about supplements a lot and I usually tell them 99% are a waste of money and to check out examine.com - very nice non-biased evidence based summaries.
I love examine.com. It's not what it used to be though.
hmm actually have not used in a while… hipefu things haven’t gone too downhill. UI certainly looks like it had an overhaul.
I don't. To me all of these findings are way to new and with too thin scientific consensus yet.
Generally I think I was born in the luckiest time of human history ever. But particularly on this topic I wish I was born more like 2080s or something. Our grandchildren might maybe use supplements like these to stay forever young.
glucosamine chondroitin for knee arthritis. Old wrestling injury. But I can still run like 50 miles a week in the 7-8 minute pace range so I’m happy for a guy in his mid 40’s!
Magnesium at night. It's a game changer
Used to take a lot of vitamin D. Should probably start doing that again.
Currently: fish oil, lion's mane, vitamins and minerals, IP6, bovine colostrum, melatonin, probiotics, D3+K2.
No supplements. But I have made a change recently which led to some HUGE health improvements. And that is the carnivore diet.
Here's my post from a while back Kinda-carnivore diet is leading to WAY more energy.
And since then it's just gotten more pronounced. Latest steps in my carnivore path - and why you should consider a carnivore diet
I should write an update. But basically- every physical, mental, and emotional marker is improving.
Carnivore calm is a term I heard today in a podcast (I'm listening to a lot of Dr. Shawn Baker's old podcasts). And it really resonated. That's what I feel. I sure wish I had started this much earlier.
For your Alzheimer's risk, sauna + maximizing insulin sensitivity is your best friend. (I'm in the same boat; just got sub-panel installed so we can get a sauna in here.)
I had a dry sauna installed when I lived in Ca and insulin sensitivity won't return my text messages.
Let me know if you solve reading in the sauna. I accepted destroying books at one point.
We need a section for supplements here on SN! I'm still building my stack but so far it's : -iron for energy -D3+k2 for calcium, I notice in my teeth -NMN - aging -Resveratrol - aging
1 cup of sperm every morning in bed! I feel like it lubricates my joints and it improves my morale every time.
That's a lot of volume. I think you just confessed to bestiality.
Or she's in the Navy.
oh my! 😆
I take hidroferol, because I have low levels of vitamin D. Nothing else, of course, since it's not only unnecessary to take any supplements when your biochemical levels are right, but it can be detrimental and even dangerous at toxic levels.
Creatine
No
I tried taking some niacin for a month but not sure I saw any benefits.
++ to NMN & Resveratrol
I've cut down on a lot of big pharma meds, and take quite the handful of trusted, personally researched natural supplements now. really too many to mention. I follow the likes of Dr. Berg, Dr. Nepute and many others on YT. they are a great help when medical docs 'in the system' literally suck, just want profit, and are unwilling to help!
I'm really interested in how Nattokanase does for you!!!
I hear it is really good for clearing blood clots, and I have a lot of circulation issues!
Please keep me updated!
any questions are welcome 🤗
For anyone who needs protection from the effects of chronic stress, I highly recommend Phosphatidyl Serine. Taking this stuff is really good for the brain and calms you down, help with sleep, lowers cortisol, makes your thinking more sharp, etc. I recommend NOW soy-free Phosphatidyl Serine containing Sharp-PS. More info:
https://www.zrtlab.com/blog/archive/phosphatidylserine-protection-from-chronic-stress/
Many report the Stamets stack, from mycologist Paul Stamets, helps with mood, PTSD , brain healing and cognitive enhancement:
Lion's mane + microdose of psilocybin mushroom + niacin
F****** NO !
I might consider taking it if the doctor prescribed it.
haha, just dumb
i've found Quercetin (with Bromelain) to be a major boost for the immune system. it's also helped my girlfriend with her seasonal allergies, replaced the need for anti-histamines.
Started taking that during the "2020 event" and never stopped 👍
Sun light, fresh air, nature. I believe we have everything we need within. No need for supplements IMO. I feel younger than I ever did when I was worried about how to stay younger with supplements.
My supplement are sunlight, grounding and beef (meat, organs, bone). Nothing fancy
Only the 3 basic ones: Protein, Creatine and some random/cheap Multi-vitamins.
Reading this comment section kinda worries me. Some people are taking too much shit with weird names.
D3
One of the best supplements out there is Longvida curcumin - an patented form of turmeric extract, developed by scientists at UCLA, that crosses the blood-brain barrier. All other turmerics just work on the body but longvida is mildly mood enhancing, clears brain fog and powerfully reduces inflammation. It also works on the body.
The stuff is like a panacea for many kinds of inflammation, mood and congitive funks: It is works well as an anti-depressant (curcumin show to be similar to SSRIs in published studies) , clears brain fog, eases aches and pains, activates the CB1 cannabinoid receptor (has a calming CBD-like effect).
A lot of Indian physicians take Longvida. I take between 500 to 2000mg a day, depending on how much of a boost I need. If I am not feeling well for almost any reason, I bump it up.
LMAO
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