People who try to lose weight often experience a Jo-Jo-effect: The lost pounds come back quickly. Scientists from the ETH Zurich now observed an obesogenic memory on a cellular level. Epigenetic changes result in altered gene transcription in adipocytes. These changes remain even after significant weight loss. This leads to a quicker weight gain and larger fat depots in formerly fat mice, compared to mice that had always been lean.

This shows how important it is to maintain a healthy bodyweight of your children. They will profit their whole lifes.