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145 sats \ 3 replies \ @nullcount 12 Dec 2023 freebie \ on: I work with a medicine we call Bufo. It comes from a toad. AMA AMA
5-MeO-DMT a.k.a. The "God Molecule"
https://psychedelicreview.com/wp-content/uploads/2019/12/3000-5-MeO-DMT-DMT-and-serotonin-2048x658.png
A naturally occurring Tryptamine, an indolamine metabolite which bonds to serotonin receptors and does not easily detach until it is broken down by enzymes in the body. Effects last 10-15 minutes but while tripping, subjects are highly neuroplastic as neurons in the brain are stimulated into forming novel pathways.
A high dose can literally change your default mode network and affect the kinds of thoughts you have medium-long term. This is why its important to consider set and setting and approach the molecule with respect and humility. The role of a shaman is to guide your mind in and out of the journey. Its a ancient therapy that according to the "Stoned Ape Theory" could have been responsible for the evolutionary development of homo sapiens' enlarged frontal cortex.
Thank you for providing this. I love connecting the science to the more esoteric sides of these things.
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What are your thoughts on synthetic 5-MeO-DMT for clinical use?
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In my experience, the bufo medicine is best sat with in the desert on the earth. The energies that come through are intense and being grounded is helpful. Science agrees with this. We are energetic beings. When I am in the medicine I am always called to earth. I have never sat in a clinical setting and I have never used a synthetic varient. To me, everything is energy. So where something come from matters. I like the thing I can trace to the earth and connect with on an energetic level. I don't know how to connect with a thing that is synthesized. To me, there is more to a thing than what our human minds and science can comprehend. So I prefer the natural setting, non clinical, more shamanic approach. But that doesn't mean that 5meo-dmt in a more clinical setting can't be great. I just like the other approach. Everyone is called to different types of experiences and at the end of the day, the best setting is the one where the participant feels safe to have the experience and connect. And that may look very different for different people. Just my opinion. Thanks for the great question.
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