Generally speaking, you don’t want a participant in a market to be able to determine the outcome unilaterally, setting other ethical concerns aside. 

denlillaapan

We try to stay away from Death market because of its unethical and violence nature. However we do permit some ethical ones like few examples below:

We will NEVER do markets like: Will [insert person name] be assassinated in 2025?

bitcoin

Where Them Cypherpunks At?! (Bitcoin Magazine, Shinobi)

We try to stay away from Death market because of its unethical and violence nature. However we do permit some ethical ones like few examples below: 

1) Assassination **attempt** is NOT equal to assassination, especially for public political figures. 
2) Death due to poor health/medical conditions
3) And Khamenei is just one-off case, though assassination is not the prime reason.

We will NEVER do markets like: Will [insert person name] be assassinated in 2025?