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One of the most common questions that I get, being carnivore, is this:
"Aren't you worried about your cholesterol?"
And there's been many good answers to that. High cholesterol is just a very bad predictor of heart attacks.
But with this new study that came out, it's pretty definitive.
The bottom line is, the factor that's really linked to heart attacks is coronary plaque. Having a high CAC score (coronary arterial calcium) is very strongly predictive of all kinds of heart disease.
This just-released study followed 100 healthy individuals on a long-term ketogenic diet (many of them carnivore). After doing the ketogenic diet, they developed very high LDL-C.
However, they didn't develop more coronary plaque. And that's the important thing.
Despite LDL-C/ApoB levels that would typically be alarming, these markers showed no association with coronary plaque progression.
Notably, 90% of participants showed no significant change in plaque over the course of one year, and remarkably, six participants showed reductions in their total plaque scores.
Baseline coronary plaque—particularly a positive CAC score—was the best predictor of future plaque growth.
The supposed association of high LDL with heart disease is the reason so many statins (a very high profit drug for big pharma) are prescribed. Statins have horrible side effects and do not work overall for reducing deaths from heart disease.
33 sats \ 0 replies \ @aljaz 8 Apr
high cholesterol psyop goes hand in hand with "you should eat as much processed food as we can produce in our chemical factories and "cows are bad for the env cuz they fart"
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The supposed association of high LDL with heart disease is the reason so many statins (a very high profit drug for big pharma) are prescribed. Statins have horrible side effects and do not work overall for reducing deaths from heart disease.
I remember the first time I heard of the Ketogenic diet many years ago and this question was a big one. Dude that was trying it out tested his blood and cholesterol and found the same thing. It seem entirely possible that the high LDL might not be the direct reason for heart disease but rather a commonality in those with the disease.
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And maybe not even a commonality. There's lot of evidence, even before this study, that higher LDL, especially in the elderly, has an INVERSE association with mortality.
I think the only commonality that exists may be that...statins, one of their most profitable drugs, will reliably lower LDL. That's why they push this high-LDL/heart disease story.
I think we're not nearly cynical enough on the cholesterol/statin/heart disease story.
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Yeah, we aren't cynical enough about incentives in medicine around drugs and doctors.
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Interesting finding but 100 people isnt a big enough study to draw hard conclusions from.
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A rigorous study of 100 people, using hard tests, as as good of a gold standard you can get. The studies "proving" that high LDL causes heart disease are not rigorous.
Also - very important point here - this study was not funded by big pharma or government (sometimes one and the same)!
Instead, it was self-funded, by a guy who went on a keto diet, felt really great afterwards but was told by his doctor that he'd die because his LDL cholesterol was so high, and decided to investigate.
Here's the group that did it - https://citizensciencefoundation.org/.
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