Qubes is great. The networking is really nice. Makes it easy to have specific VMs run through tor or a vpn (for example) or to have VMs that dont have network connections or only have connections to specific VM. This is all standard virtual networking, but qubes has some nice tooling around it. 

rijndael

bitcoin

Malicious Python Packages Replace Crypto Addresses in Developer Clipboards

One of many reasons why I always recommend that devs (and others) use QubesOS: https://www.qubes-os.org/intro/

tl;dr: it splits everything up into a bunch of virtual machines. In this case it'd protect your clipboard from being seen at all by the malware, if you split your dev VMs from your btc VMs 