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66 sats \ 1 reply \ @oliverweiss 21h \ parent \ on: The Ozempic Shortage Is Over HealthAndFitness
Interesting. The question is if the blindness was really caused by the drug, I mean it is known that obesity may lead to diabetes and diabetes to blindness. It could just be that the drugs didn’t really work, the patients developed diabetes…
I can also imagine that some people at Novo Nordisk got nervous by this news 😬
Even if there is a higher association of NAION caused by these drugs, I would want to know how that compares to the greater risk of diabetic retinopathy. I have seen NAION less than a handful of times, whereas I see diabetic retinopathy and other complications of diabetes every day.
Too lazy to look up actual numbers with cited sources but O1 vibe check says:
NAION: Often cited around 2–10 per 100,000 persons per year (for individuals over 50). Diabetic Retinopathy : Multiple large-scale studies (e.g., NHANES in the United States) have reported that anywhere from 20% to 40% (or more) of people with diabetes show some level of retinopathy Putting It All Together:
- NAION in diabetics: Elevated risk vs. non-diabetics, but still a relatively uncommon event.
- Diabetic Retinopathy (and its advanced stages) is very common in long-standing diabetes—often cited as the leading cause of new cases of blindness among working-age adults in many countries.
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