In a coinjoin every participant has to sign the transaction. If just one participant fails to do that within the time limit, the entire process of input/output registration and finally transaction signing is restarted. So yes this does in fact happen. The higher the number of participants, the likelier it is to fail. You probably don't even notice when using Wasabi Wallet since all that happens automatically.

If you bring Lightning channel opens into the mix, then you have even more potential for failure. A Lightning channel involves two parties. So the other party also has to cooperate with the channel commitment in order for the coinjoin transaction to be signed by the participant funding the channel.