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“e.g., the Crimea region of Ukraine”
Good example of how stupid sanctions get. Russia itself – the economy responsible for the invasion of Ukraine – is not sanctioned yet the invaded part of Ukraine is.
It makes farm more sense to apply broad, common sense, sanctions where they really make sense (obviously, if you're doing trade with Russia right now you're funding an invasion), and redirect the money wasted on this massive bureaucracy to just blowing up enemy assets.
Ukrainian drone attacks on Russian oil refineries has been more effective than all other sanctions combined. Case in point: https://oilprice.com/Latest-Energy-News/World-News/Ukrainian-Drone-Attacks-Disrupt-Key-Russian-Oil-Export-Route.html