This year has seen significant breakthroughs in various fields, including medicine, space exploration, genetics, and astronomy. Some of the key discoveries include: HIV Prevention Drug Lenacapavir with a 96-100% success rate in preventing HIV/AIDS; Completed Map of Fruit Fly Brain, which could help understand human brain function; New Super-Earth Found In a Habitable Zone, a potentially habitable planet 137 light-years away; Neanderthal and Human Breeding Timeline, pinpointing when humans and Neanderthals interbred; CRISPR and AI Team Up, using AI to make gene editing more accurate and safer; Detecting Cognitive Decline With a Blood Test, a simple blood test with 88-92% accuracy in detecting Alzheimer's; Oldest Known Reptile Skin Found, a 20-million-year-old fossilized reptile skin; and The New Moons of Neptune and Uranus, three new moons discovered orbiting these ice giants. These discoveries have the potential to revolutionize our understanding of the world and improve human lives.