Difficulty was 1 at genesis time.

Hashes / sat was 0.8 at genesis time. (4 billion hashes / 5 billion sats)

Hashes per sat now is (napkin math, 4 halvings) 100 trillion * 2^4 * 0.8

Naive: buying bitcoin with energy got more expensive by about 1.6 quadrillion times. More nuance: actually more like only a trillion because the transition to asics was about 1000x more energy efficiency. (I don't know the actual efficiency factor, but I think this is a decent guess.)