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Certainly there is no publicly released client software configured for mainnet
The mercury client code can be configured to use mainnet statecoins by simply setting network = "bitcoin" in the client's Settings.toml file, so it's not that hard to set up. In fact, to demonstrate the vulns to mercury I double-spent some mainnet coins after ostensibly "transferring" the statecoin UTXO to Tom. But it would take a conscious effort to do that, in spite of blatant warnings to the contrary.
Really I have no idea if there are any mainnet users, but I find it unlikely. See tom's post below for more info