Once humans have the ability to settle elsewhere in the solar system, if bitcoin adoption continues to grow, then we can expect to see a major changes to the bitcoin ecosystem.
Mining requires a lot of energy and so far we've seen those with the cheapest, most abundant, usable energy stack the most sats. In fact, you can make up for outdated equipment if your energy is cheap enough. If humans settle outside of Earth, then we'd have the tech to run mining equipment in space running on solar power.
If there are colonies on Mars and in the asteroid belt then roughly half the time they'll be on the other side of the Sun from the Earth, so it seems natural that mining equipment would organize centrally in a tighter orbit around the Sun. Those closest to the Sun have higher energy densities and lower latencies between nodes and would have the lowest average latency communicating with the various colonies around the solar system.
Whoever can manufacture the most mining rigs and deploy in a tight orbit around the Sun, would have the most hashrate, so if bitcoin continues gaining value like it has in the past then we'd expect an arms race to capture sunlight. Could this motivate the construction of a Dyson sphere [1]?
In this scenario there are likely far more humans than we currently have and therefore much greater demand for on-chain settlement. Due to limited transaction throughput on chain and the high latencies in interplanetary communication [2] we can expect the vast majority of transactions to take place on higher layers.