I was never sceptic of childhood vaccines until the covid vaccines arrived. I wanted to know more about childhood vaccines and I read the first 2 chapters of Turtles All The Way Down: Vaccine Science and Myth that described in detail about it's never tested against a placebo, among others. That was for me the point to not take anymore vaccines for my kids.
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Clinical trials using children as subjects must be tricky and possibly unethical
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That's a non-starter. You can't even use women in most clinical trials, because they might get pregnant. Clinical trial selection is actually a huge methodological rabbit hole, if you want to get into some really concerning weeds.
There are other experimental designs that could be used, though. One is what's called "Intent to Treat" where one group is given an extra reminder to keep up with the vaccine schedule. Then you use the difference in compliance rates to evaluate the schedule.
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By the time I had started looking into it we had already made most of our vaccine choices. With my current understanding, I would have spaced them out a little more and maybe pushed back stronger on a couple.
I'll keep that book in mind. I've been wanting a good resource for this.
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