Most people around here probably know that using USB peripherals is a giant security risk; however, in normal life it's pretty hard not to use them, at least if you're interfacing with the rest of humankind.
So imagine this scenario: someone, who is probably a good actor gives you a USB drive with some data on it. You want to transfer this data to your computer. You have modest ability to be paranoid, e.g., you could have a spare computer, some kind of dongle, whatever. You don't, however, have the ability to be extremely paranoid (e.g., you get a disposable computer for each USB you plug in.)
What should you do? I'm looking for practical advice to solve a practical problem.
Footnotes