Lots of angles to this.
  • How long do you want to move? 3 years or 10 years?
  • Do you have a job lined up? Stable source of income?
  • Is your partner on board with this? Will she/he be working/staying home?
  • How old are your kids? Younger kids adjust more easily.
  • Do you plan on learning the language? Do you already speak the language?
  • Do you want to live in the expat community or do you want to mingle with locals? The expat community is usually more expensive.
  • Have you ever lived abroad? How different is the new culture from your current cultural background?
To answer your question, how well your kids will adjust will mostly depend on how well-prepared you are. My biggest worry about moving will be more about how well my partner than how well my kid will adjust. He'll be fine.