It's an hard question, there is a lot of solutions and there isn't a "LN-friendly front end framework". Firstly, do you want to build an API/Frontend stack or a more classical MVC stack? This simple question can determine if you need to learn a frontend framework like vue, react or any other JS front end framework.

For example, you can do "MVC" with Django (a web framework for python). I don't know python neither django, but I know it provides you a view rendering engine.

If you prefer to work with an API and a JS frontend framework, I think (and it's personal) Vue.js is a good option. It's easy to learn and fun. There is also a SSR option using Nuxt.js (it's a framework on top on Vue.js), but it's a little bit more advanced.

To conclude, keep in mind there is no better front end framework for LN stuff. Since your app run in your browser, everything you can do in JS can be done with any frontend framework (or view engine in case of MVC stuff)

I hope it will help you in your choice