I will never sell for the purpose of accumulating a different store of value, such as gold or (lol) USD. However if I want something bad enough, and the only way I can get it is by parting with some of my stack, I certainly would consider it. The annoying extra step of converting to the local currency first is irrelevant if it's necessary to get what I want. But as long as I have value that needs storing, Bitcoin is the only option.