I use qubes as a daily driver, it's actually really handy to separate work stuff from other projects

QubesOS has wonderful security by way of jt's novel approach to virtualizing application workdlows, but it's a PITA to setup and use so I often avoid using my Qubes rig if I don't have to.

For my daily driver, I find that I much prefer VanillaOS. See the other comment for details.