I don't think this is true for cryptography. At least nothing comes to mind thinking about it rn.
I think this quote was not meant super serious. However, I think it has some truth to it which can be applied everywhere:
For example, just by asking simple questions (what is the block size of bitcoin? how is the 21M limit enforced?) you can easily dismiss people who want to argue about bitcoin but don't know the answers to these questions.
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