I don't see anything at the base layer, I know there's one or two consensus cleanup items that need a patch eventually, but even that narrative has been diluted by people that want to bundle in a bunch of non-critical items and spread fear so people act hastily.

If something is imminently critical, and real, the fix must be acute. In that scenario it will have no problem getting consensus. Ossification is a straw man they loom over people to say if we don't fix things the way they want today we'll never fix them.

Mining centralization is at spooky levels, but that's a market condition that is transient and already healing by the day.

Distribution is a concern, but not critical. That's a reflection of the real world economy, so again market driven, not technical.

Culture/incentives are probably the biggest risk, there's very few principled people that have the ability to do principled things. Fortunately, bitcoin's technical design is literally built to mitigate that cultural/incentive risk. Every time a script kiddie or NGO wants to change Bitcoin I appreciate it for what it is even more.