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Not a Wise idea.
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If you can't send funds to Ghana because your Wise account no longer lets you, then sending using bitcoin through one of the many methods (e.g., Bitnob), is a great alternative.
Those in the U.S. can use Strike's Send Globally, to send directly to the Ghanian's mobile money phone number (MTN or Vodafone).
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Wise (formerly Transferwise) is one of the more popular payment methods used for trading bitcoin person-to-person (P2P).
Ghana has been facing a severe economic crisis that triggered a restructuring of its local debts last week. The country also announced a deal with the IMF for a $3 billion bailout.

The currency strengthened to 9.5 to the dollar in a fourth straight session of gains, though is still down nearly 40% since the start of the year, Refinitiv data showed.

Yes, you might say the exchange rate has been volatile lately:
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