It is for sure the biggest hurdle of air travel. I use to travel regularly to 2 locations for work, one by air, one by train. Air journey: leave home super early or super late (2 flights per day only), 10min walk to train station, 45min by train, 2h wasted at airport for security, customs, boarding, waiting, 45min flight, 15-20min to get out and reach train station. 45-60min by train to hotel in city center or to working place. Alternative was 8-9h by train.

By train to second location: 10min walk to train station, train already here, take seat, leave 10min later top. 3h of train with large seats, table and wifi access, I could work all travel or rest really for a couple of hours. Get off of train, walk 10min to hotel in city center. 10-15min by street car to working place outside center. Oh and there were trains every 2h and I could change train often up to the last minute with few or no fee.

Wonder which travel I would prefer.